This site provides educational information on current research, scientific exploration, and emerging evidence related to manual and robotic-assisted microsurgery and potential applications in neurosurgery, lymphatic surgery for brain disease, and spine procedures.
Lymphatic Reconstruction
for Brain Disease
Investigating robotic-assisted microsurgical approaches for anastomosis of deep cervical lymph nodes to veins to improve brain waste drainage. First in human procedure completed April 2026.
Intracranial
Surgery
Investigating robotic-assisted microsurgical approaches to brain surface bypass and EDAS procedures to revascularize the brain. First in human procedure completed September 2025.
Spine
Surgery
Evaluating robotic-assisted microsurgical approaches for select spine procedures for dissection of soft tissues.
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The information provided is solely for educational purposes relating to scientific information on neuro and spine research.
The REMIND study describes an investigational use of the Symani Surgical System. The investigational use of the Symani Surgical System described herein has been approved by the FDA under the Code of Federal Regulations Title 21 Part 812 as an Investigational Device Exemption.
The safety and effectiveness of the Symani Surgical System for lymphatic reconstruction for brain disease has NOT been established by any regulatory agency.
The Symani Surgical System is indicated in the U.S. for soft tissue manipulation in open microsurgical procedures to perform:
- Anastomosis, suturing, and ligation microsurgery techniques on small blood vessels and lymphatic ducts between 0.1 and 2.5mm in open free-flap surgery of the breast, mouth, scalp, and extremities and in open lymphatic surgery of the extremities.
- Dissection of soft tissues.
Clinical indications vary by geography. Refer to global indications for more information. For risks, cautions, warnings, and full prescribing information, please reference Symani safety and performance information.
